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Cytoplast™ Ti-250 Titanium-Reinforced Non-Resorbable High-Density PTFE Membranes

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Customer Testimonials

In my experience, this membrane may be the best on the market currently for treatment of the severely resorbed extraction socket. It provides predictable space maintenance, and excellent bone regeneration potential.

Matt Heaton Ti

An excellent choice in GBR options. I can do many more cases because of these barrier options.

Ward Fitzpatrick, DDS, Periodontist

This product is great for socket preservation, ridge augmentation, and periodontal defects. Surgical results are wonderful. Membranes are easy to manage and hold their integrity well. Excellent product & great value, can't beat that combination.

Eric Guirguis, Ti

I have done great bone regeneration procedures using the titanium reinforced membranes. I can also use around a stable implant with buccal bone missing. The membrane holds up creating quality bone and tissue. They can be easily removed.

Craig Thiede, Ti

The ease of use, the quick adaptability with good stability after placement convinced me of their superior product.

Dewey Carter, Ti

This is a very high quality product that consistently produces predictable results in my practice. It is a product any implant surgeon should consider in their armamentarium.

David H. Gilbert, Ti

Cytoplast™ Ti-250 Titanium-Reinforced Non-Resorbable High-Density PTFE Membranes

  • 250 microns thick
  • Non-resorbable high-density PTFE membrane
  • Ideal for ridge augmentation and grafting bony defects missing one or more walls
  • Membrane can be molded and shaped for tenting and space maintenance
  • Titanium frame may be trimmed and shaped to create additional space for bone growth
  • Regentex™ surface is designed to increase surface area available for soft tissue attachment

 

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More Information

Often used with on-lay grafting in ridge augmentation procedures, Cytoplast™ Ti-250 titanium-reinforced membranes provide clinicians with the predictability they are accustomed to with the Cytoplast™ TXT-200 membranes, along with the added benefit of a titanium frame to maintain space during guided bone regeneration. These membranes are also popular for adding structural support when grafting 3 or 4-walled extraction sites.

 

The textured Regentex™ surface is designed to increase the surface area available for cellular attachment, thereby assisting in stabilization of the membrane and prevention of soft tissue retraction.

 

With sixteen different membrane configurations, little trimming is necessary to fit a variety of defect sizes. However, the membranes can be trimmed according to clinicians’ needs.

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Products

Procedures

Copyright © 2025 Osteogenics Biomedical, All rights reserved

Design and Developed by devoqdesign

Published Studies

Effectiveness of vertical ridge augmentation interventions: A systematic review and meta-analysis.
Urban I, Montero E, Monje A, Sanz-Sánchez I.

J Clin Periodontol. 2019 Jun;46 Suppl 21:319-339.

Decision Tree for Vertical Ridge Augmentation.
Plonka AB, Urban IA, Wang HL.

Int J Periodontics Restorative Dent. 2018 Mar/Apr;38(2):269-275.

Principles for Vertical Ridge Augmentation in the Atrophic Posterior Mandible: A Technical Review.
Urban IA, Monje A, Lozada J, Wang HL

Int J Periodontics Restorative Dent. 2017 Sep/Oct;37(5):639-645.

Surgical Management of Significant Maxillary Anterior Vertical Ridge Defects.
Urban IA, Monje A, Nevins M, Nevins ML, Lozada JL, Wang HL.

Int J Periodontics Restorative Dent. 2016 May-Jun;36(3):329-37.

Expanded vs. dense polytetrafluoroethylene membranes in vertical ridge augmentation around dental implants: a prospective randomized controlled clinical trial.
Ronda M, Rebaudi A, Torelli L, Stacchi C.

Clin Oral Implants Res. 2014 Jul;25(7):859-66.

A Proposal of Pseudo-periosteum Classification After GBR by Means of Titanium-Reinforced d-PTFE Membranes or Titanium Meshes Plus Cross-Linked Collagen Membranes.
Cucchi A, Sartori M, Aldini NN, Vignudelli E, Corinaldesi G.
Int J Periodontics Restorative Dent. 2019 Jul/Aug;39(4):e157-e165.
The influence of wound closure on graft stability: An in vitro comparison of different bone grafting techniques for the treatment of one-wall horizontal bone defects.
Mertens C, Braun S, Krisam J, Hoffmann J.

Clin Implant Dent Relat Res. 2019 Apr;21(2):284-291.

Buccal bone thickness adjacent to virtual dental implants following guided bone regeneration.
Phillips DJ, Swenson DT, Johnson TM.

J Periodontol. 2019 Jun;90(6):595-607.

Management Of 80 Complications In Vertical And Horizontal Ridge Augmentation With Nonresorbable Membrane (d-PTFE): A Cross-Sectional Study.
Gallo P, Díaz-Báez D.

Int J Oral Maxillofac Implants. 2019 July/August;34(4):927–935.

Peri-implant diseases: Current understanding and management.
Barootchi S, Wang HL.

Int J Oral Implantol (Berl). 2021 Aug 20;14(3):263-282.

Dense Polytetrafluoroethylene Membrane versus Titanium Mesh in Vertical Ridge Augmentation: Clinical and Histological Results of a Split-mouth Prospective Study.
Maiorana C, Fontana F, dal Polo MR, Pieroni S, Ferrantino L, Poli PP, Simion M.

J Contemp Dent Pract 2021; 22 (5):465-472.

Guided bone regeneration in staged vertical and horizontal bone augmentation using platelet-rich fibrin associated with bone grafts: a retrospective clinical study.
Amaral Valladão CA Jr, Freitas Monteiro M, Joly JC.
Int J Implant Dent. 2020 Oct 17;6(1):72.
Guided Bone Regeneration with Nonresorbable Membranes in the Rehabilitation of Partially Edentulous Atrophic Arches: A Retrospective Study on 122 Implants with a 3- to 7-Year Follow-up.
Pistilli R, Simion M, Barausse C, Gasparro R, Pistilli V, Bellini P, Felice P.

Int J Periodontics Restorative Dent. Sep/Oct 2020;40(5):685-692.

Vertical ridge augmentation (VRA) with Ti-reinforced d-PTFE membranes or Ti meshes and collagen membranes: 1-year results of a randomized clinical trial.
Cucchi A, Vignudelli E, Fiorino A, Pellegrino G, Corinaldesi G.

Clin Oral Implants Res. 2020 Oct 5. <Epub ahead of print>

Published Case Series

A Case Series of Vertical Ridge Augmentation Using a Nonresorbable Membrane: A Multicenter Study.
Mendoza-Azpur G, Gallo P, Mayta-Tovalino F, Alva R, Valdivia E.
Int J Periodontics Restorative Dent. 2018 Nov/Dec;38(6):811-816.
Vertical Ridge Augmentation and Soft Tissue Reconstruction of the Anterior Atrophic Maxillae: A Case Series.
Urban IA, Monje A, Wang HL.

Int J Periodontics Restorative Dent. 2015 Sep-Oct;35(5):613-23.

Partial lateralization of the nasopalatine nerve at the incisive foramen for ridge augmentation in the anterior maxilla prior to placement of dental implants: a retrospective case series evaluating self-reported data and neurosensory testing.
Urban I, Jovanovic SA, Buser D, Bornstein MM.

Int J Periodontics Restorative Dent. 2015 Mar-Apr;35(2):169-77.

Vertical Guided Bone Regeneration using Titanium-reinforced d-PTFE Membrane and Prehydrated Corticocancellous Bone Graft.
Cucchi, Ghensi.

Open Dent J. 2014 Nov 14;8:194-200. (Article is open access)

Vertical ridge augmentation with titanium-reinforced, dense-PTFE membranes and a combination of particulated autogenous bone and anorganic bovine bone-derived mineral: a prospective case series in 19 patients.
Urban IA, Lozada JL, Jovanovic SA, Nagursky H, Nagy K.
Int J Oral Maxillofac Implants. 2014 Jan-Feb;29(1):185-93.
The Creation of Attached Gingiva Immediately After Extraction - Bone augmentation procedure without wound closure.
Grundemann L, Vroom M.

Tandartspraktijk. January 2015.

Renewed non-resorbable membranes - Bone augmentation techniques.
Vroom M, Grundemann L.

Dentista, February 2017.

Ridge preservation/restoration using d-PTFE membranes.
Vroom M, Grundemann L.

Inspyred: The alternative EAO voice. Volume 6, Issue 1: Summer 2018.

Alveolar Ridge Augmentation Around Exposed Mandibular Dental Implant with Histomorphometric Analysis.
Ibraheem AG, Blanchard SB.

Clin Adv Periodontics. 2020 Jan 22.

Regeneration of Peri-implantitis Infrabony Defects: Report on Three Cases.
Wen SC, Huang WX, Wang HL.

Int J Periodontics Restorative Dent. 2019 Sep/Oct;39(5):615-621.

Management of the exposure of a dense PTFE (d-PTFE) membrane in guided bone regeneration (GBR): a case report.
Ghensi P, Stablum W, Bettio E, Soldini MC, Tripi TR, Soldini C.

Oral Implantol (Rome). 2017 Jul-Sep; 10(3): 335–342.

Vertical Ridge Augmentation Around Dental Implants With the Use of a Dense PTFE Membrane to Correct Previously Failed Augmentations.
Soldatos N, Garcia M, Umoh E, Irizarry A, Weltman R.

Clin Adv Periodontics. 2021 Sep 23.

Vertical bone augmentation utilizing a titanium-reinforced PTFE mesh: A multi-variate analysis of influencing factors.
Urban IA, Saleh MHA, Ravidà A, Forster A, Wang HL, Barath Z.

Clin Oral Implants Res. 2021 Jul;32(7):828-839.

Vertical-guided bone regeneration with a titanium-reinforced d-PTFE membrane utilizing a novel split-thickness flap design: a prospective case series.
Windisch P, Orban K, Salvi GE, Sculean A, Molnar B.

Clin Oral Investig. 2021 May;25(5):2969-2980.

Posters

Coronal Advancement of the Lingual Flap.
Dr. Paolo Rossetti

Presented at the European Academy for Osseointegration (EAO) in Rome Italy, September 25-27, 2014

Treatment of an Infected Exposure of a Dense Polytetrafluoroethylene Membrane in a Vertical Guided Bone Regeneration Procedure: A Protocol Proposal.
Fabrizio Belleggia, DDS
Presented at the European Academy for Osseointegration (EAO) in Rome Italy, September 25-27, 2014
The Pros of the Staged Approach in Vertical Guided Bone and Soft Tissue Reconstruction of the Mandibular Atrophy.
Fabrizio Belleggia, DDS
Presented at the European Academy for Osseointegration (EAO) in Rome Italy, September 25-27, 2014
Horizontal and Vertical Bone Augmentation with Titanium Reinforced d-PTFE Membranes: Case Series in 8 Patients.
Cakir S., Gultekin B.A., Cinar I.C., Guven G., Saglanmak A., Karabuda Z.C., Yalcin S.

Presented at the EAO in Rome Italy, September 25-27 2014

Esthetic Rehabilitation of Anterior Teeth Following Traumatic Avulsion
André CorreiaDMD, PhD , Manuel Neves DMD ; Zsolt Kovacs LDT

Presented at the ITI World Symposium in Geneva, April 24 - 26, 2014

Clinical Evaluation of Guided Bone Regeneration Procedures Using a dense-Polytetrafluoroethylene Membrane. A Preliminary Report.
Fabrizio Belleggia, DDS

Presented at the SIO in Italy, 2012

Vertical Ridge Augmentation Using Reinforced PTFE Mesh Versus Customized Titanium Mesh. Preliminary Results Of A Randomized Clinical Trial.
Bettini S, Rengo C, Fiorino A, Cucchi A.

Poster presented at the 2020 IAO in Milan Italy.

Unpublished Case Reports

Ridge augmentation with immediate implant placement using a high-density titanium-reinforced PTFE membrane.
Marco Ronda, DDS
The use of tenting screws with high-density titanium-reinforced PTFE membrane.
Joel L. Rosenlicht, DMD
Guided bone regeneration using a high-density titaniumreinforced PTFE membrane and corticocancellous block graft
Joel L. Rosenlicht, DMD
Immediate implant placement and socket reconstruction using a high-density titanium-reinforced PTFE membrane.
Barry K. Bartee, DDS, MD
Minimally Invasive Socket Reconstruction Using A High-Density Titanium-Reinforced Ptfe Membrane
Barry K. Bartee, DDS, MD
Cytoplast™ PTFE Membrane Brochure
Cytoplast™ Ti-250 & Ti150 Technical Information
Osteogenics Regenerative Products Catalog
Cytoplast™ Titanium-Reinforced PTFE Membranes Instructions For Use